Simplifying single-molecule fluorescence spectroscopy
Developing a range of tools built on our expertise in single-molecule detection, to benefit life science research in academia and pharma diagnostics.
EI-FLEX, simplifying single-molecule spectroscopy
An affordable bench-top instrument capable of two-colour, single-molecule fluorescence detection in solution.
The EI-FLEX is a versatile tool for studying protein conformations and biomolecular interactions. Now smFRET and FCS experiments are accessible at your benchtop without optical tables or dark rooms.
Real-time data analysis and visualisation.
Democratising single-molecule biophysics
Single molecule spectroscopy is a powerful technique that could lead to new discoveries in biophysics, life sciences, drug development and diagnostics. We set out to democratise this cutting-edge approach, and bring it to the widest possible user base. Ultimately we hope to make our instrument a standard tool in every biophysics lab.
Applications
Protein conformational landscapes
Verifying protein structure
Verify that the static protein structures obtained from crystallography, cryoEM or AlphaFold are the major species present in the solution.
Binding and diffusion
Investigate the binding and disassociation of biomolecular complexes, including protein-protein interactions, ligand-receptor binding (GPCRs) and Extracellular Vesicles (EVs).