📘 Discover everything you need to understand in-solution smFRET and use it to advance your research

Download handbook now
Contact us
Contact us

Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation

Author

Jessica May Price

Format

Paper

Chadda et al. Nucleic Acids Research, Volume 52, Issue 19, 28 October 2024, Pages 11626–11640, https://doi.org/10.1093/nar/gkae584
Download now
Tags
Technology
smFRET
Applications
DNA structure
Protein-DNA interactions
Protein structure and dynamics
Replication
DNA repair

Recent posts

Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Discover how smFRET data from EI-FLEX visualises real-time RNA synthesis by SARS-CoV-2 RdRp and reveals how antiviral inhibitors remodel polymerase dynamics to halt viral replication.
Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation
Discover how smFRET data from the EI-FLEX reveals how RPA partially wraps single-stranded DNA and remodels its structure through phosphorylation.
Precision and accuracy of single-molecule FRET measurements
Discover how the landmark Hellenkamp et al. study set the standard for precise, reproducible single-molecule FRET measurements using DNA rulers.