📘 Discover everything you need to understand in-solution smFRET and use it to advance your research

Download handbook now
Contact us
Contact us

Delineation of a novel assembly intermediate in retroviral integration pathway

Author

Jessica May Price

Format

Preprint

Rahul Chadda, Sibes Bera, Mohamed Ghoneim, Tamara De Melo, Duane P. Grandgenett, Edwin Antony, Krishan K. Pandey

bioRxiv 2025.09.09.675266; doi: https://doi.org/10.1101/2025.09.09.675266
Download now
Tags
Technology
smFRET
Applications
Protein structure and dynamics
Enzymes
Protein-DNA interactions
DNA structure

Recent posts

Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Discover how smFRET data from EI-FLEX visualises real-time RNA synthesis by SARS-CoV-2 RdRp and reveals how antiviral inhibitors remodel polymerase dynamics to halt viral replication.
Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation
Discover how smFRET data from the EI-FLEX reveals how RPA partially wraps single-stranded DNA and remodels its structure through phosphorylation.
Precision and accuracy of single-molecule FRET measurements
Discover how the landmark Hellenkamp et al. study set the standard for precise, reproducible single-molecule FRET measurements using DNA rulers.