📘 Discover everything you need to understand in-solution smFRET and use it to advance your research

Download handbook now
Contact us
Contact us

Precision and accuracy of single-molecule FRET measurements

Author

Jessica May Price

Format

Paper

Hellenkamp, B., Schmid, S., Doroshenko, O. et al. Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study. Nat Methods 15, 669–676 (2018). https://doi.org/10.1038/s41592-018-0085-0

Download now
Tags
Technology
smFRET
Applications
DNA structure

Recent posts

Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Discover how smFRET data from EI-FLEX visualises real-time RNA synthesis by SARS-CoV-2 RdRp and reveals how antiviral inhibitors remodel polymerase dynamics to halt viral replication.
Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation
Discover how smFRET data from the EI-FLEX reveals how RPA partially wraps single-stranded DNA and remodels its structure through phosphorylation.
Precision and accuracy of single-molecule FRET measurements
Discover how the landmark Hellenkamp et al. study set the standard for precise, reproducible single-molecule FRET measurements using DNA rulers.