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Home
Products
EI-FLEX Pro
EI-FLEX
Technology
Applications
By application area
Protein-DNA interactions
Protein-RNA interactions
Protein structure and dynamics
Antibody-antigen interactions
Riboswitches
Motor proteins
Enzymes
DNA structure
G-quadruplexes
Ternary complexes
By research goal
Resources
Resource overview
Resource library
About
Management
Careers
Home
Products
EI-FLEX Pro
EI-FLEX
Technology
Applications
By application area
Protein-DNA interactions
Protein-RNA interactions
Protein structure and dynamics
Antibody-antigen interactions
Riboswitches
Motor proteins
Enzymes
DNA structure
G-quadruplexes
Ternary complexes
By research goal
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19 December 2025
Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET
Format
Paper
Groves et al.
Nucleic Acids Research
, Volume 53, Issue 8, 8 May 2025, gkaf351,
https://doi.org/10.1093/nar/gkaf351
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Customer data
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Delayed termination
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EI-FLEX
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Molecular motors
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Polymerase stalling
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Protein–RNA interactions
,
Replication
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RNA polymerase
,
Single-molecule kinetics
,
smFRET
,
Transcription
Technology
smFRET
Applications
Protein structure and dynamics
Replication
Protein-RNA interactions
RNA structure
Enzymes
Enzymes
Recent posts
Delineation of a novel assembly intermediate in Rous sarcoma virus integration pathway
EI-FLEX data revealed a transient tetrameric intermediate in retroviral DNA integration.
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Understanding protein-dependent RNA pseudoknot formation with single-molecule FRET on the EI-FLEX system
Dive into the mechanisms of protein-dependent pseudoknot formation, and see how smFRET adds crucial dynamics to structural data.
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Kinesin-1 is highly flexible and adopts an open conformation in the absence of cargo
Discover how EI-FLEX smFRET reveals pH-driven DNA triplex nanoswitching and confirms that dynamic DNA machines retain fast, reversible conformational control even when densely immobilised on electronic surfaces.
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