Exciting Instruments’ groundbreaking benchtop single-molecule detection platform brings the ultimate resolution to life science research, drug development and clinical diagnostics. The company is bringing in a new era where single-molecule insights become the foundation for scientific breakthroughs that lead to rapid and meaningful improvements in human health.
Today, Exciting Instruments announced the launch of PhotonFit, a streamlined software platform designed to remove long-standing technical barriers to smFRET, FCS, and FCCS data processing.
For years, scientists have been forced to navigate a complex analysis pipeline, relying on fragmented open-source code, manual dependency management, and disconnected Jupyter Notebooks. These hurdles have not only slowed the pace of discovery but have deterred many from attempting single-molecule experiments altogether.
Redefining the analysis workflow
PhotonFit introduces several features designed for speed and transparency:
- Go from sample to results in minutes: No setup, no coding, no terminal commands – just start analysing immediately in a ready-to-use environment designed for scientists across the life sciences.
- Discover insights in real-time: Use intuitive controls to explore and refine data with instant visual feedback, while comparing samples side by side.
- Go from raw photos to final figures: Export high-quality visuals and complete datasets in seconds, ready for sharing, reporting, and publication without extra work.
- Open-source file format: The high-performance HDF5 format ensures raw data files contain necessary metadata, meaning they are FAIR and immediately ready for AI-driven pipelines and cross-modality research.
Dr. Janice D. Pata, Director of the Division of Scientific Cores at Wadsworth Center, New York State Department of Health, said:
“In the past, my team spent more time troubleshooting open source software packages than actually looking at their data. PhotonFit has completely removed that friction. The interface is intuitive, and the sliding scales for real-time parameter tuning give us immediate confidence in our results. It has turned complex, manual analysis into a same-day discovery session, allowing us to focus on the biology instead of the code.”
Tim Craggs, CEO and Founder of Exciting Instruments, added:
“We saw brilliant scientists losing time to complicated code instead of focusing on their science. With PhotonFit, we’ve removed the computational complexity, allowing researchers to concentrate on biological insights rather than the underlying code. Whether you are a career biophysicist or a biochemist in a drug-discovery lab trying single-molecule techniques for the first time, the path from raw photons to publication-ready fits is now open to all.”
By removing the barrier to entry, PhotonFit allows labs to scale their research without needing a dedicated software specialist on staff. This release reaffirms Exciting Instruments’ commitment to making powerful biophysical tools accessible to the broader scientific community.
For more information about PhotonFit and The Exciting Ecosystem, visit our website.
Want to chat to about PhotonFit or contact the team for comment? Email info@excitinginstruments.com for more information.
